Pharmaceutical class

Oral hypoglycemic drug

Drug form

10 mg and 25 mg tablets

Drug combinations

empagliflozin

Mechanism of action of Gloripa

This drug is considered as a glucose-sodium reabsorption inhibitor drug, which reduces blood sugar by inhibiting glucose reabsorption in the kidney.

Uses of Gloripa

This drug is used in type 2 diabetes to control blood sugar and reduce the risk of death from cardiovascular diseases in patients with diabetes and cardiovascular diseases.

Use in pregnancy and breastfeeding:

Pregnancy: Adequate and well-controlled studies have not been conducted in pregnant women. The use of this medicine is not recommended especially during the second and third months of pregnancy.
Lactation: There is no information available about the secretion of this drug in human milk. Due to the possibility of serious side effects in infants, its use during breastfeeding is not recommended.

Regarding the correct way to take the medicine, pay attention to these points:

1- Take this medicine exactly as prescribed by the doctor. Sometimes the doctor may change the dosage of the medicine if needed.
2- Take this medicine once a day in the morning, with food or on an empty stomach.
3- Simultaneous use of this drug with other antidiabetic drugs may be recommended by the doctor. In such a situation, blood sugar can drop.
4- In stressful conditions such as fever, trauma (such as a car accident), infection or surgery, the amount of medication may be changed.
5- When taking this medicine, follow the diet and exercise recommended by the doctor.
6- Diabetes control is done by the doctor by performing regular periodical tests, including determination of blood sugar and hemoglobin HbA1c.
7- Consult your doctor about how to prevent, identify and control low blood sugar (hypoglycemia), high blood sugar (hyperglycemia) and problems related to diabetes.
8- While taking this medicine, sugar may be seen in the urine.
9- Consult your doctor about consuming more fluids.
10- In order to be more effective and also to remember the daily intake, take this medicine every day at a specific time.
11- If you forget to take a dose of medicine, take it immediately as soon as you remember. But if it is almost time to take the next dose, take only that dose and avoid doubling the amount of medicine.

Gloripa drug interactions:

Before taking this medicine, inform your doctor if you are using the following medicines:

Androgens (except danazol), insulin and other hypoglycemic drugs, pegisomant – with concomitant use of drugs, the hypoglycemic effect of empagliflozin may increase.
Systemic corticosteroids, danazol, somatropin – the hypoglycemic effect of empagliflozin may be reduced with concomitant use of drugs.
Deloxetine, levodopa – with the simultaneous use of drugs, the effect of lowering blood pressure may increase due to the use of these drugs.
Antihypertensive drugs – side effects and toxicity of other antihypertensive drugs may increase with simultaneous use of drugs.
Luteinizing hormones, hormone-secreting analogs, thiazide diuretic drugs – the therapeutic effect of empagliflozin may decrease with simultaneous use of drugs.

Precautions Gloripa

1- This medicine may cause confusion in some people. This effect may be intensified when taken at the same time with alcohol or some drugs. Therefore, during the treatment, avoid driving and working with devices that require complete alertness.
2- Empagliflozin may cause confusion, dizziness or syncope. The possibility of these effects may increase, especially in simultaneous use with alcohol, very hot weather, exercise or fever. To avoid these effects, sit or stand slowly, especially in the morning.
3- Always carry your ID card that shows you have diabetes.
4- Follow the diet and exercise program prescribed by the doctor. Correct diet, regular exercise and regular blood sugar testing have an effective role in the effectiveness of this medicine.
5- Control the amount of blood sugar according to the doctor’s order. If blood sugar increases or decreases while taking this medicine, consult your doctor.
6- Do not increase the amount of medicine without a doctor’s order.
7- It may be more difficult to control blood sugar in stressful conditions such as fever, infection, injury or surgery. In such a situation, consult your doctor and avoid changing the amount of medicine without his prescription.
8- When taking this medicine, especially in hot weather or during physical activity, be careful of losing water in your body. Dehydration may increase the possibility of empagliflozin side effects.
9- In case of vomiting or diarrhea, contact your doctor to prevent dehydration.
10- Before performing any medical or dental care, medical emergency or surgery, inform your doctor or dentist about the use of this medicine.
11- This drug usually does not cause low blood sugar, but if it is used simultaneously with other blood sugar lowering drugs such as insulin and sulfonylureas, it may cause blood sugar to drop. Symptoms of low blood sugar include anxiety, sweating, weakness, confusion, drowsiness, syncope, rapid heartbeat, vision changes, headache, tremors, and hunger. Taking some fast-acting sugars such as glucose tablets or gels is useful for treating low blood sugar. If you don’t have access to these substances, eating or drinking quick sources of sugar such as sugar cubes, honey, candy, orange juice or non-diet soda helps. In order to avoid low blood sugar, eat meals at specific times during the day and do not miss any of the meals.
12- This medicine makes the urine sugar test positive. Therefore, before doing this test, inform your doctor about the use of this medicine.
13- While taking this medicine, perform tests related to blood cholesterol level, kidney function, fasting blood sugar and hemoglobin A1c. These tests are done to monitor the disease or control side effects. Therefore, see a doctor at regular intervals.

Gloripa contraindications

Hypersensitivity to empagliflozin or any of the ingredients of this medicine
Severe renal failure
Dialysis patients
End stage of kidney disease
Type 1 diabetes
Diabetic ketoacidosis (increased ketones in the blood or urine)

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