Fosfestrol is an estrogen used in the treatment of estrogen replacement in cases such as vaginitis, ovarian insufficiency, primary ovarian failure and in the treatment of metastatic carcinoma of the breast and prostate.
Mechanism of action of Fosfestrol Estrogens bind to specific receptors to make proteins that are responsible for the effects of these drugs. Estrogens reduce the levels of FSH and LH hormones by reducing the release of LHRH.
Pharmacokinetics of Fos Festerol Metabolism of this drug is hepatic and is mainly excreted by the kidneys.
Should not be used for breast cancer (non-metastatic), obstructive jaundice, estrogen-dependent neoplasms, thromboembolic diseases, and bleeding of unknown genital tract.
FosFesterol Side Effects
Menstrual irregularities and gastrointestinal disorders are side effects of the drug.
- Irregular bleeding
- nausea and vomiting
- Digestive disorders
- stomach ache
- Menstrual disorders
- Mood swings
- Change in body weight
- Breast tenderness
- Breast enlargement
- Sexual dysfunction
Consult your doctor if you have any other symptoms that you feel may be due to Fosfestrol.
FosFesterol Drug Interactions
Concomitant use of estrogens with oral anticoagulants may reduce the effects of these drugs. Concomitant use of toxic drugs for the liver aggravates liver damage. Concomitant use of estrogens with phenobarbital, carbamazepine, phenytoin reduces the effects of estrogens. Taking estrogen with tricyclic antidepressants increases the serum concentration of these drugs. Estrogens reduce the antihypertensive effects of antihypertensive drugs.
Estrogen use in men may cause breast cancer.
Due to the effect of estrogens on the closure of the epiphysis, the use of this drug in immature children should be done with great caution.
In the presence of endometriosis, gallbladder disease, high blood calcium, porphyria or fibroids should be used with caution.
Fosfestrol does not cause blurred vision or drowsiness and does not affect your ability to drive. You do not need to avoid driving or operating machinery while using this medicine.
FosFesterol Medication Recommendations
- Estrogen therapy should be started with the lowest dose.
- Except in special cases (such as cancer treatment) Estrogen therapy should be taken periodically (such as 3 weeks of drug use and one week of non-use).
- Estrogen therapy may cause nausea, especially in the morning. Consumption of solid foods usually relieves this condition to some extent.
- Pay attention to the expiration date of Fos Festerol and do not take it if your medicine has expired.
- Never give Fos Festerol to another person, even if you have the same symptoms.
- Check for Fos Festerol drug interactions, and if you are using a drug that interacts with this drug, talk to your doctor about using your medications.
- Complete Fos Festerol Pharmacological Information
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