Stomach acid inhibitor
20 and 40 mg enteric coated capsules
S-omeprazole (as magnesium trihydrate)
Mechanism of action of Ezonium:
Proton pump inhibitor
Uses of Ezonium:
By reducing acid production in the stomach, this medicine is used for reflux diseases, gastric ulcer, duodenal ulcer, erosive esophagitis, Helicobacter pylori infection, Zollinger-Ellison syndrome, reducing the possibility of stomach ulcer caused by non-steroidal anti-inflammatory drugs. A dose of 20 mg of ozonium is considered a non-prescription medicine.
Use in pregnancy and breastfeeding Ezonium:
Pregnancy: Adequate and well-controlled studies have not been conducted in pregnant women. It is allowed to use this medicine during pregnancy under the supervision of a doctor if there is a definite need for it.
Lactation: The secretion of this drug in human milk has not been studied so far. Due to the possibility of serious side effects in infants, its use during breastfeeding is not recommended
Regarding the correct way to take the medicine, pay attention to these points:
1- Take this medicine at least one hour before food.
2- Swallow the capsule completely, avoid crushing, breaking or chewing it. If you are unable to swallow the capsule completely, open it, spread the contents in a tablespoon of fruit compote or yogurt and eat it immediately. In addition, the pellets can be mixed with some water or fruit juice and eaten immediately. You can use apple juice or orange juice as fruit juice. Avoid chewing and crushing the contents of the capsule.
3- Take this medicine for the full treatment period even if you feel better.
4- If you forget to take a dose of medicine, take it immediately as soon as you remember. But if it is almost time for the next dose, forget the missed dose and resume your normal schedule. Avoid doubling the amount of medicine.
Ezonium drug interactions:
Before taking this medicine, inform your doctor if you are using the following medicines:
Amoxicillin and clarithromycin – simultaneous use may increase the amount of omeprazole and hydroxyclarithromycin in the blood.
Azole antifungal drugs (such as itraconazole, ketoconazole) – the use of omeprazole increases the pH of the digestive system and may reduce the absorption of these drugs. Concomitant use of drugs is prohibited.
Benzodiazepines (such as diazepam, triazolam) – in simultaneous use, the amount of benzodiazepines in the blood increases. It is recommended to reduce the amount of benzodiazepines or increase the intervals between the two drugs.
Clopidogrel – Antiplatelet activity of clopidogrel may decrease with concomitant use of drugs.
Digoxin – simultaneous use of drugs may increase the amount of digoxin in the blood.
Erlotinib – the use of omeprazole may interfere with the absorption of erlotinib. The combined use of drugs should be avoided.
Methotrexate – omeprazole may increase the amount of methotrexate in the blood by reducing the renal excretion of methotrexate, thus increasing the risk of toxicity with it. In case of simultaneous use of drugs, determining the amount of methotrexate in the blood and the symptoms caused by drug toxicity should be carefully monitored.
Mycophenolate – the amount of mycophenolate in the blood and its pharmacological effects may decrease.
Sustained-release tolterodine – The release of tolterodine from the sustained-release form of the drug may increase due to the increase in gastric pH after taking omeprazole. It is necessary to adjust the dose of tolterodine.
Salicylates with enteric coating – salicylates may dissolve faster and the gastrointestinal side effects caused by their consumption may be aggravated.
Warfarin – simultaneous use may increase INR and prothrombin time and lead to abnormal bleeding and even death. Therefore, changes in INR and prothrombin time should be monitored.
Precautions for Ezonium:
In order to control the progress of the treatment, visit your doctor regularly.
If the condition does not improve or worsens, consult your doctor.
History of allergy or anaphylaxis to any of the components of this medicine
– History of allergy to benzimidazole substitute drugs (rabeprazole, pantoprazole and omeprazole)
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