Pharmaceutical class:
Anti-depressant, anti-anxiety
Drug form:
Tablets of 10 and 20 mg
Drug combinations:
S. Citalopram
Mechanism of action of Ezipam:
Selective serotonin reuptake inhibitor
Uses of Ezipam:
Major depressive disorder, generalized anxiety disorder, obsessive compulsive disorder, panic disorder and social anxiety disorder.
Use in pregnancy and breastfeeding Ezipam:
Pregnancy: Adequate and well-controlled studies have not been conducted in pregnant women. Therefore, the use of this medicine during pregnancy should be done under the supervision of a specialist doctor and with caution if there is a definite need for it.
Lactation: This drug is secreted in human milk. Due to the possibility of excessive sleepiness, loss of feeling and weight loss in infants, its use during breastfeeding is not recommended.
Pay attention to these points regarding the correct way to take the drug Ezipam:
- Use this medicine only according to the doctor’s prescription. Avoid taking more, frequent and longer doses than prescribed by the doctor.
- This medicine can be taken with food or on an empty stomach according to the doctor’s order.
- Symptoms of recovery may appear 1 to 4 weeks after starting to take the drug.
- Do not stop taking the medicine without consulting your doctor.
- If you forget to take the medicine, consult your doctor.
Ezipam drug interactions:
Before taking this medicine, inform your doctor if you are using the following medicines:
Alcohol – Do not drink alcoholic beverages with this medicine at the same time.
Tricyclic antidepressants – it is necessary to observe caution when using drugs together.
Carbamazepine – this drug may increase the excretion of citalopram.
Drugs affecting the central nervous system (CNS) – the simultaneous use of these drugs and citalopram should be done with caution.
Cimetidine – with the simultaneous use of drugs, the amount of citalopram in the blood increases.
Citalopram-S citalopram is the active isomer of racemic citalopram, so they should not be used together.
Ketoconazole – with the simultaneous use of ketoconazole and racemic citalopram, the amount of ketoconazole in the blood decreases.
Linezolid – Serotonin syndrome has been reported when used simultaneously with citalopram.
Lithium – since lithium may increase the effects of citalopram, concomitant use of drugs should be done with caution. The amount of lithium in the blood should be monitored and adjusted.
Metoprolol – when taken together with citalopram, the amount of metoprolol in the blood increases.
Medicines that inhibit monoamine oxidase – simultaneous use of medicines is prohibited. With their combined use, serious and sometimes fatal side effects have been reported. At least 14 days should be allowed between stopping the use of one drug (e.g. citalopram or monoamine oxidase inhibitor) and starting the other drug.
Non-steroidal anti-inflammatory drugs such as aspirin and other drugs effective on coagulation – when used together with citalopram, there is a possibility of upper gastrointestinal bleeding. Caution is essential.
Sumatriptan – weakness, hyperreflexia (excessive reaction) and imbalance have been reported in some patients with the combined use of drugs. In case of simultaneous use of drugs, full monitoring of the patient’s condition is recommended.
Warfarin – Prothrombin time may increase with concomitant use of drugs.
Drugs with serotonergic activity (such as buspirone, fentanyl, lithium, sumatriptan, duloxetine, amitriptyline, tramadol, tryptophan) – the risk of serotonin syndrome, a rare but potentially fatal reaction, increases if taken concurrently.
Ezipam precautions:
1- During the use of this medicine, visit your doctor regularly to check the progress of the treatment, possible changes in the amount of medicine and to help reduce unwanted side effects.
2- Avoid taking this medicine together with or within 14 days of stopping taking a monoamine oxidase medicine (isocarboxazid, phenelzine, selegiline, tranylcypromine). Also, avoid taking a monoamine oxidase drug within 14 days of stopping taking citalopram. Otherwise, very high blood pressure or convulsive attacks may occur.
3- The use of this medicine may cause confusion, irritability or other abnormal behaviors in some people. In some people, this drug may cause suicidal thoughts and tendencies or more depression. Contact your doctor immediately if you notice any of these side effects.
4- Avoid drinking alcoholic beverages with this medicine at the same time.
5- This medicine may cause drowsiness, thought disorder or movement problems in some people. Therefore, during treatment, avoid driving and working with equipment that requires full alertness.
Ezipam contraindications:
History of allergy to citalopram or citalopram and any of the components of this medicine
– Concomitant treatment or within 14 days of discontinuing the use of a monoamine oxidase inhibitor such as selegiline (used in the treatment of Parkinson’s disease), meclobemide (used in the treatment of depression) and linezolid (antibiotic)
– Starting treatment in patients previously treated with linezolid or methylene blue intravenous injection
– Concomitant use with pimozide
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