angiotensin converting enzyme (ACE) inhibitor
5 mg and 20 mg tablets
Mechanism of action of Enalapril:
This drug prevents the conversion of angiotensin I to angiotensin II by inhibiting angiotensin converting enzyme.
Uses of Enalapril:
Use in pregnancy and breastfeeding Enalapril:
Pregnancy: It is forbidden to use this medicine during pregnancy, especially in the second and third trimesters.
Breastfeeding: This drug passes through breast milk, so its use during breastfeeding is not recommended.
Regarding the correct way to take the medicine, pay attention to these points:
1- Take this medicine every day exactly as prescribed by the doctor, at a specific time during the day. Avoid taking more amounts and times than prescribed by the doctor.
2- During treatment, control your weight and diet, especially sodium consumption. Avoid using salt substitutes or milk containing low amounts of sodium without a doctor’s prescription.
3- In some patients, the symptoms of high blood pressure may not be seen. In such a situation, the use of medicine should be continued even with the feeling of recovery.
4- This medicine does not cure high blood pressure, but it helps to control it, and it may be necessary to take it for the whole life. Therefore, consult your doctor before stopping the medication. Not treating high blood pressure is associated with serious risks.
5- If you forget to take a dose of medicine, take it immediately as soon as you remember. But if it is almost time for the next dose, forget the missed dose and resume your normal schedule. Avoid doubling the amount of medicine.
Enalapril drug interactions:
Before taking this medicine, inform your doctor if you are using the following medicines:
Soft drinks containing alcohol, diuretics or other blood pressure lowering drugs – blood pressure lowering effects may be increased.
Nonsteroidal anti-inflammatory drugs, especially indomethacin – simultaneous use of these drugs with enalapril may reduce the antihypertensive effect of enalapril.
Blood from the blood bank, cyclosporine, potassium-containing diuretics, low-salt milk, potassium-containing drugs, potassium supplements or substances containing high concentrations of potassium or salt substitutes – the simultaneous use of enalapril with these drugs may lead to hyperkalemia (increased potassium in the blood). ) will be The simultaneous use of these drugs in patients with congestive heart failure is not recommended.
Allopurinol, cytotoxic drugs, procainamide, systemic corticosteroids, bone marrow depressant drugs – simultaneous use of these drugs with enalapril may lead to an increased possibility of neutropenia (decrease in white blood cells) or agranulocytosis.
Lithium – in simultaneous use with enalapril, a reversible increase in serum lithium levels and drug toxicity have been reported.
Sympathomimetic drugs – simultaneous use may reduce the antihypertensive effects of these drugs.
1- In order to control the progress of the treatment, change in the amount of medication and control unwanted side effects, visit your doctor at regular intervals.
2- In case of possible pregnancy or becoming pregnant, inform your doctor immediately. Taking this medicine, especially during the second and third trimesters (after the first 3 months) of pregnancy, may lead to serious injury or even death of the unborn baby.
3- Avoid taking other medicines, supplements containing potassium, or salt substitutes containing potassium, unless the doctor has ordered it.
4- After taking the first dose of the drug, especially if it is combined with a diuretic drug, confusion, dizziness or syncope may occur. Therefore, avoid driving and working with equipment that requires full alertness.
5- In case of syncope or dizziness while taking the medicine, inform your doctor.
6- If symptoms such as fever, sore throat or chills are observed; Inform your doctor. These symptoms can be a sign of the spread of infection due to the decrease in the number of white blood cells.
7- Consult your doctor if you notice problems in breathing or swelling of the face, arms or legs. These symptoms may be signs of a serious allergic reaction.
8- If you get sick while taking this medicine, especially if it is accompanied by severe or continuous vomiting or diarrhea, inform your doctor. This condition may cause excessive dehydration and possibly lead to low blood pressure.
9- Exercising or being in very hot weather may lead to dizziness, fainting, or syncope. Excessive sweating with excessive loss of body water can cause a drop in blood pressure. Therefore, it is recommended to take care of yourself while exercising or in very hot weather.
10- Black patients may be less sensitive to the blood pressure lowering effects of this drug. In addition, the possibility of serious allergic reactions such as swelling of the face, mouth, hands or feet may increase.
11- Before performing any surgery (including dental surgery) or emergency treatment, inform your doctor or dentist about the use of this medicine.
1- History of allergy to any of the components of this medicine
2- Patients with a history of angioedema related to previous treatment with an angiotensin-converting enzyme inhibitor drug
3- Patients with hereditary or idiopathic angioedema
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