How to take Depofem ampoules

To start taking combination ampules, the person who has chosen this method to prevent pregnancy should be checked by a gynecologist for the possibility of absolute and relative contraindications to the use of ampules. Also, in this visit, breast examination and examination of the person for jaundice Takes. Measurement of blood pressure, height and weight is essential at the first visit. The volunteer has 3 months to have a blood test for triglycerides and a Pap smear. In some people, additional tests are needed.
The first injection should be given at the beginning of this method in one of the first 5 days of menstruation and the next 30 days after the previous one. However, in case of emergency, the injection can be given 3 days earlier or 3 days later than scheduled. The injection is given intramuscularly in the upper arm or buttock muscle. The injection site should not be massaged.
The person using this method should refer to the service center after three months from the beginning of use and then once every 6 months for two years to perform the necessary examinations. If you do not have the problem of annual visits, it is enough to continue using this method to prevent unwanted pregnancies.

Tests and examinations required for contraceptive injection

Depofem First referral

Examination of the client for jaundice,
Blood pressure measurement,
Height and weight measurement for BMI (body mass index),
Breast examination,
Pap smear test (4-6 weeks after delivery and according to national guidelines),
Evaluation of coagulation problems and blood lipids (in case of history of thrombosis or heart disease in first degree relatives under 50 years),
If the applicant’s triglyceride is more than 250 mg / 100 ml at the beginning of the combined ampoules, a retest will be performed 2-4 weeks after the combined ampoule injection. If the triglyceride rises to more than 500 mg per 100 ml during this period, continued use of the combined ampoules will be discontinued due to the possibility of pancreatitis.

Second visit

The first examination is done after 3 months and then every 6 months for up to two years, and after that, if there are no problems, it is done every year as follows:
Blood pressure measurement,
Weight measurement,
Follow-up of warning signs and complications and, if necessary, check them,
– A closer look at women with a chronic condition for which the effect of the injection is not known (diseases that are not mentioned in the case of contraception).
– If any of the above problems exist, it should be referred to a gynecologist.
Annual testing of sugar, fat and lipoprotein for the following women is done in follow-up visits:
-Women 35 years and older.
Women with a history of heart disease or high blood pressure.
Women with a history of gestational diabetes.
– Obese women
– At each visit for the next injection, you should be asked about satisfaction with the method, complaints, warnings or side effects.

Benefits of one month injection

1- High effectiveness (in the first year of using every 1000 couples who use this method, 998 couples will definitely not get pregnant.)
2- It is easy to use and if you decide to stop taking it, there is no need for special action, and in most cases, ovulation and the possibility of pregnancy return to normal 2 to 3 months after the last injection.
3- It has no effect on sexual desire.
4- Since this method does not require daily consumption; Therefore, it is suitable for women who give the possibility of forgetfulness in timely consumption, or women who are nomads, or cases such as mental retardation, etc.
5- The effectiveness of this method does not decrease in case of diarrhea and vomiting (compared to combination pills) and can be used simultaneously with the use of antibiotics (except rifampin and grisofulin).
6- Injection of combined contraceptive ampoules reduces menstrual bleeding, thus reducing the possibility of anemia following heavy menstruation.
7. Consumers of combined contraceptive pills are less likely to experience the effects of weight gain and irregular bleeding compared to users of combined contraceptive pills.
8- Women who have a history of ectopic pregnancy can use this method. In addition, combined contraceptive pills have little effect on the coagulation system.
It should be noted :
– This method does not prevent sexually transmitted diseases and AIDS.

Do not use Cyclofem or Depofem for one month

  • Pregnant or suspected women
  • Women who gave birth less than 3 weeks ago if they are not breastfeeding “If breastfeeding is best not to use this method for six months.”
  • Women with uterine bleeding for no apparent reason
  • Suspected breast cancer, or history of uterine cancer
  • Ms. Smoker 35 years and older
  • Women with active or chronic liver disease
  • Some heart diseases; Vascular with a doctor’s diagnosis
  • Stroke and cerebrovascular disease
  • Diabetes in certain conditions
  • Blood pressure above 100/160 mm Hg
  • Some severe headaches diagnosed by a doctor
  • Increased blood lipids
  • One month before each operation until the end of the immobility period

Possible side effects of Cyclofem or Depofem ampoules

Serious side effects of taking birth control pills are rare, but the user should be familiar with them.
Mild headaches that can be relieved with regular painkillers such as aspirin, ibuprofen or acetaminophen.
Mild weight gain is due to the accumulation of fluid in the body due to the effect of the hormone progesterone and increased appetite, followed by increased food intake, which can be relieved by regular exercise and diet.
Breast tenderness, which is usually relieved by following health recommendations such as the use of tight braces and the use of hot or cold compresses and the use of conventional painkillers such as aspirin, ibuprofen or acetaminophen.
In case of acne, it can be eliminated by changing the diet, such as reducing the amount of fat consumed, especially fatty snacks, and increasing the consumption of fresh and clean fruits and vegetables, keeping the skin clean.
Mood swings and depression can be relieved by continuing to take ampoules. If these symptoms persist for more than three months, it is important to see a doctor.
Decreased amount and number of menstrual bleeding days may also occur in some cases.
Severe or prolonged irregular uterine bleeding is uncommon and usually resolves within the first 2 to 3 months of injection. For short-term relief, a non-steroidal anti-inflammatory drug can be used (such as ibuprofen 800 mg three times a day for 5 days with heavy bleeding)
If the problem persists or severe or prolonged bleeding or severe or prolonged bleeding begins after several months of using these ampoules with normal menstrual bleeding or menopause, it is necessary to see a gynecologist.
Menopause after injection of contraceptive pills is not common. If it happens, it is necessary to see a gynecologist for training, counseling and necessary examinations. Of course, 80% of women who stop menstruating by taking quarterly contraceptive pills start their period by changing the method to combined one-month ampoules.

Injection warnings

If you experience any of the following symptoms, you should see a doctor or health center immediately:
Severe pain in the upper abdomen, chest pain, shortness of breath or cough with bloody sputum, severe or throbbing headache or pain in one side of the head, eye problems (blurred vision, double nose or loss of vision), swelling Or severe pain in one leg and jaundice of the mucous membranes of the eyes and skin

Notes when consuming

  1. Cyclofem or Depofem injection should be given every 30 days. If the applicant comes up to 3 days earlier or 3 days later than scheduled, cyclofem can be injected while emphasizing the need to comply with the specified time. The total interval between injections should not exceed 33 days.
  2. The ampoule or vial should be gently shaken before inserting the ampoule into the syringe. If the ampoule or vial is cold, it should be adjusted to body temperature before injection. Rubbing the ampoule or vial between the hands will help.
  3. In case of delay for the next injection (more than 33 days), it will be possible to perform the injection with the assurance of not having sexual contact (after 33 days until the time of referral) or to ensure that the person is not pregnant. Otherwise, the person should be checked for pregnancy and use another adjuvant method until the next injection

Fertility return after discontinuation of the injection method

In most cases, recurrence of ovulation occurs 2-3 months after the last injection.


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