What is Corizan?

It relieves pain and fever caused by colds and sinusitis and is used to relieve nasal congestion, allergies and runny nose.Corizan tablet is a medication used for the treatment of various health conditions such as allergies, itching, and rashes. This medication is available as an over-the-counter (OTC) product, which means it can be purchased without a prescription. However, it’s important to understand the potential side effects, usage, dosage, and restrictions before taking this medication.

Corizan Tablet Drug Combination

160 mg acetaminophen plus 2.5 mg phenylephrine hydrochloride plus 5.5 mg diphenhydramine hydrochloride in 5 ml.

Corizan mechanism of action

Cyclooxygenase inhibitor, decongestant, antihistamine

Corizan Use in pregnancy and lactation


Occasional use of this drug does not appear to cause problems in the fetus or newborn, although taking larger doses or taking it for a longer period of time may increase the risk. This drug is allowed to be taken by a doctor during pregnancy.


This drug is excreted in breast milk and may cause unwanted side effects such as excitement or abnormal irritability in the infant, while it may also reduce milk flow. Therefore, its use during breastfeeding is not recommended.

About how to take the right medicine

  1. Use this medicine only as directed by your doctor or medication guide. Avoid taking large amounts or more times as directed by your medication.
  2. This medicine can be taken with food or on an empty stomach.
  3. Use the dose with this medicine to measure the dose.
  4. If you miss a dose, take it as soon as you remember. But if it ‘s almost time for your next dose, just take that dose and avoid doubling the dose.

Corizan Drug Interactions

Tell your doctor before taking this medicine if you are taking any of the following medicines.
Beta-blockers (such as propranolol), furazolidone, indomethacin, isoniazid, monoamine oxidase inhibitors (such as phenelzine), tricyclic antidepressants (such as amitriptyline) – these may increase the risk of side effects. .
Anticoagulants (such as warfarin), digoxin – may increase the risk of bleeding, irregular heartbeat or heart attack.
Bromocriptine or hydantoin drugs (such as phenytoin) – The risk of side effects from these drugs may increase.
Guanadrel, guanthidine, mecamylamine, methyl dopa, reserpine – Concomitant use of these drugs may reduce their effectiveness.

Corizan Precautions

  • The results of skin tests performed to diagnose allergies may be affected by the use of this drug. Therefore, it is necessary to inform the doctor about the use of this drug before performing any of the above tests.
  • If the symptoms do not improve within 5 to 7 days of taking the drug or they get worse or you see a high fever that lasts more than 3 days, consult your doctor.
  • Consult your doctor if you have a severe sore throat or sore throat that lasts more than 2 days or is accompanied by fever, headache, skin rash, nausea and vomiting.
  • In case of alcohol abuse; Taking other antihistamines or drugs that affect hay fever, other allergies, and colds; Painkillers, sedatives or sleeping pills; Over-the-counter or over-the-counter painkillers; Barbiturates; Anticonvulsant drugs; Muscle relaxants; Anesthetics, including dental anesthetics, consult your doctor.
  • Concomitant use of this drug with large amounts of alcoholic beverages may cause liver damage.
  • This drug may cause drowsiness, dizziness, blurred vision and loss of consciousness in some people, so while treating, avoid working with devices that require full consciousness.
  • This medicine may cause anger, restlessness, or difficulty falling asleep in some people. If you have trouble falling asleep, take the last daily dose of this medicine a few hours before bedtime.
  • This drug may increase the stimulatory effects of diet drugs on the central nervous system. Therefore, do not use this drug at the same time with diet or appetite control drugs without a doctor’s prescription.
  • Inform your doctor or dentist before taking any surgery (including dental surgery) or other urgent medical treatments.
  • This medicine may cause dry mouth, nose and throat. To temporarily relieve dry mouth, sugar-free candy or chewing gum, melting ice cubes in the mouth, or saliva substitutes can be used.
  • Tell your dentist if dry mouth persists for more than 2 weeks. Prolonged dry mouth may increase the risk of dental and gum disease and fungal infections.
  • Concomitant use of this drug with other drugs containing acetaminophen may lead to poisoning.
  • This medicine may make the skin more sensitive to sunlight. Use sunscreen or cover if exposed to sunlight for long periods of time.

Corizan prohibited usage

1- History of allergy to any of the components of this drug
2- Newborn or premature babies
3- Asthma attacks
4- Severe hypertension, severe coronary heart disease, rapid heartbeat, severe heart disease
5- Problems in urination
6- Concomitant use or during the last 14 days with furazolidone or monoamine oxidase inhibitors such as phenelzine
7- Sedatives: Taking Corizan tablet with sedatives may increase drowsiness and sedation.
8-Antidepressants: Corizan tablet may interact with certain antidepressants, such as tricyclic antidepressants (TCAs), and increase the risk of side effects.
9-Alcohol: Drinking alcohol while taking Corizan tablet may increase the risk of drowsiness and dizziness.
10-Other Antihistamines: Taking Corizan tablet with other antihistamines may increase the risk of drowsiness and other side effects.

Uses of Corizan cold syrup

This syrup comes in a 120 ml bottle, and each 5 ml contains 67 mg of chlorpheniramine and 10 mg of pseudoephedrine hydrochloride. Antihistamine in this product reduces runny nose, anti-congestion relieves cough, and acetaminophen treats fever and pain. In general, this syrup helps to improve the following symptoms:

Runny and stuffy nose
Sneezing and coughing
Muscle pain, sore throat and earache
This syrup can be used by adults as well, but during pregnancy and breastfeeding, it must be used with the doctor’s advice.


The dosage of the above product for children depends on the child’s weight and is prescribed by the doctor, but in general, the dosage is as follows:

Children 2 to 6 years: half a tablespoon every 4 to 6 hours

Children 6 to 11 years: two tablespoons every 4 to 6 hours

Does Corizan cold syrup have side effects?

Corizan syrup, if used according to the doctor’s prescription and in the mentioned amounts, usually has no side effects or the side effects are very mild (like a little sleepiness), but in case of taking more than the prescribed dose, symptoms such as stomach upset, headache and Dizziness, blurred vision and drowsiness are associated.

In what cases should we not use this syrup?

This syrup is contraindicated in patients treated with monoamine oxide inhibiting drugs. Also, if a person is allergic to the components of this product, he should avoid eating it. Newborn or premature babies, lactating women and people who are facing the symptoms of bladder neck obstruction, stomach obstruction and black water should not use Corizan cold syrup.

Side effects of Corizan tablets

In this section, we mention a list of possible side effects that may be caused by all the ingredients in Corizan tablets in the body. Of course, this list is not comprehensive and complete. There is a possibility of these side effects occurring as a result of taking Corizan tablets, and not necessarily all of them will be caused by this drug. Some of these side effects may be rare but serious. If you notice any of these side effects in your body, see your doctor immediately, especially if these side effects remain in your body for a while.

Increased or irregular heart rate
feeling anxious
Feeling of pressure in the chest
stomach ache
muscle weakness
Ringing in the ears
blurred vision
Low blood pressure
Corizan tablets may have other side effects that are not included in this list.

If you experience other side effects other than those mentioned in this list, contact your doctor immediately for medical attention.

Drug interactions with Corizan tablets

If you are also using other drugs or over-the-counter medicinal products at the same time as Corizan tablets, the effects of this tablet may change. This issue can increase the risk of side effects of this drug or prevent the proper functioning of this drug in the body. Tell your doctor about all the medications, vitamins, and herbal supplements you take so that he can help prevent or control drug interactions in your body. Corizan tablets may also interact with other drugs or pharmaceutical products:

Antipsychotic drugs
Interference with certain tests
Juxtapid mepomersen

Contraindications for Corizan tablets

One of the contraindications for taking cold pills is having a severe allergy. In addition, you should not use Corizan tablets if you have any of the following conditions:

a. Children under four years old
b. liver failure
P. Severe sensitivity
T. Taking monoamine oxidase inhibitor drugs

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