Common name:




卡托普利( Chinese)



Carbamazépine (French)

Կապտոպրիլ (Armenian)

What is Captopril Pills?

Captopril is a drug used to treat the symptoms of high blood pressure (especially in heart failure). Today, this drug is also used in patients with cardiac ischemia. It blocks the conversion of angiotensin I to angiotensin II by inhibiting the angiotensin-converting enzyme. Angiotensin II is a potent mediator that narrows blood vessels and retains sodium and water in the body. By preventing narrowing of the arteries and fluid retention in them, captopril reduces the pressure inside the blood vessels and the workload of the heart. This drug is excreted in the urine.

side effects Captopril

Central nervous system: dizziness, fainting, headache, lethargy, fatigue.

Cardiovascular: tachycardia, hypotension, angina pectoris.

Gastrointestinal tract: anorexia, taste disturbance, nausea, vomiting, abdominal pain, constipation, dry mouth.

Blood: leukopenia, agranulocytosis, pancytopenia, anemia, thrombocytopenia.

Respiratory: dry cough (persistent, itchy, without sputum), shortness of breath.

Skin: urticarial rash, papular macular rash, pruritus, alopecia.

Other complications: fever, angioedema of the face and lower extremities, increased blood potassium.

Poisoning and treatment Captopril

Clinical manifestations: severe hypotension.
Treatment: Gastric emptying should be performed by forcing the patient to vomit or gastric lavage and then administering activated charcoal to reduce drug absorption. Subsequent treatments are usually symptomatic and supportive. In severe cases, hemodialysis may be considered.


Additional tips on taking Captopril tablets

It does not cure high blood pressure, it does control it, so it may take a long time.
– While taking this drug, it is important to follow a diet and limit sodium intake.
Maintain your weight in proportion to your height and bones. Get help from your doctor if you need to lose weight.
– If you are a smoker, quit smoking. Ask your doctor to refer you to a smoking cessation counselor or group.
– Do not drink alcohol.
Take your blood pressure every week and make a note of it somewhere and show it to your doctor when you see it.
You should not take other medicines without the consent of your doctor, especially medicines for colds and coughs and stimulants while taking this medicine.
– You should not stop taking the medicine without consulting your doctor.
– The use of this drug can enter breast milk, but its safety has not been proven; Therefore, it should be used with caution.

Dosage and timing of Captopril

The dose and dose of this drug is completely dependent on the severity of the disease and the body’s response of patients.
Captopril is started at a low dose of 12.5 to 25 mg per day and can be increased to 100 mg per day at intervals of one to two weeks if needed.
This drug is usually taken twice a day, but depending on the dose of the drug and the severity of the patient’s symptoms, it can be increased to two or three times a day.
There is no particular preference for taking the drug day and night.
The best time to take the medicine is one hour before a meal.

Interaction with other drugs

Drug interaction means that the use of drugs or other drugs prescribed for heart or non-heart disease can reduce or increase the effect of this drug by various mechanisms. For example, some drugs increase the breakdown of the drug in the liver or increase excretion by the kidneys and reduce the effect of the drug. In contrast, some other drugs reduce the breakdown or excretion of the drug and increase the effect of the drug in the body.

Drugs that are considered as interactions should not cause concern or arbitrary discontinuation of the drug. If you are taking these medicines at the same time, consult your doctor as soon as possible.

  • Lozartan
  • isinopril
  • Spironolactone
  • Triamterene
  • Prazosin
  • Tamsulosin
  • Digoxin

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