Uses of Bismuth Citrate
Bismuth is used to treat stomach and intestinal ulcers and along with other drugs in the treatment of Helicobacter pylori gastrointestinal infections.
Mechanism of action of bismuth Citrate
This drug neutralizes stomach acid to some extent and may have a direct anti-Helicobacter effect. It also partially stimulates the production of prostaglandins in the stomach and duodenal walls.
Pharmacokinetics of bismuth Citrate
It is absorbed in small amounts from the gastrointestinal tract and its plasma concentration usually increases after prolonged consumption. This drug is excreted by the kidneys, but some of it may be stored in bone and other tissues.
Contraindications to the use of bismuth Citrate
This drug should not be used in renal failure.
Side effects of bismuth Citrate
May cause black tongue or stools. Nausea and vomiting have also been reported after taking this drug.
Drug Interactions Bismuth Citrate
If taken concomitantly with omeprazole, the absorption of this drug increases. It also reduces the absorption of tetracyclines.
Warnings Bismuth Citrate
- Use with caution in the elderly and people with mild renal insufficiency.
- Although this drug is co-administered with tetracycline, it can reduce their effectiveness.
Bismuth Citrate Drug Recommendations
- If the drug is prescribed with tetracyclines, it should be taken at least one hour apart.
- See a doctor if you experience gastrointestinal complications, severe nausea and vomiting.
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