What is betamethasone lotion?
Betamethasone is a steroid and prevents the release of some substances in the body that cause inflammation. Betamethasone lotion (for skin) is used to treat inflammation and itching caused by diseases such as eczema, psoriasis, and allergic reactions.
What are the uses of betamethasone lotion?
Betamethasone is used for the symptomatic treatment of severe allergic or inflammatory skin disorders such as eczema that do not respond to other weaker corticosteroids, types of dermatitis, insect bites, and psoriasis.
Mechanism of action of betamethasone
This drug is connected to its specific receptors in the cytoplasm through the cell membrane, and the drug-receptor complex enters the cell nucleus. By binding to certain areas of DNA, this complex stimulates the process of mRNA transcription, followed by the production of inhibitory enzymes, which are believed to be responsible for anti-inflammatory inhibitory effects.
Pharmacokinetics of betamethasone
The metabolism of corticosteroids mainly takes place in the skin itself, but the skin metabolism of this drug is less than other topical corticosteroids. For this reason, its repeated prescription causes the accumulation of the drug in the skin and can lead to the prolongation of the effect, the aggravation of the side effects, and the increase in the systemic absorption of the drug. The drug also has liver metabolism.
General instructions for using betamethasone lotion
In case of previous allergy to betamethasone or other corticosteroids or other cases such as allergy to preservatives, colors and food.
In case of pregnancy or breastfeeding
In children and the elderly
In case of other diseases such as infection at the site of consumption, skin atrophy, cataract, glaucoma, diabetes mellitus, herpes and tuberculosis.
How to use betamethasone lotion
The dosage of each drug is determined by the doctor, but the usual dosage and method of taking this drug is as follows:
Gently massage a sufficient amount of lotion on the affected area once or twice a day.
If you forget each dose, take the medicine immediately after you remember. Note that you should not take twice the amount of medicine in one dose.
Complete the course of treatment and do not take more than prescribed by the doctor.
Medicines should be prescribed by a doctor and should not be used longer than the prescribed period for treatment. This medicine is for external use and contact with eyes, mouth or vaginal use should be avoided.
No other medication containing corticosteroids should be used with this lotion without consulting a doctor.
The skin of the area treated with this lotion should not be bandaged without a doctor’s opinion.
Amount of betamethasone lotion
In adults, it is used 1-2 times a day on the position, and in children, it is used only once a day.
Use of betamethasone lotion during pregnancy and breastfeeding
Local use of this lotion during pregnancy or breastfeeding, especially for a long time, or in large areas, or in large amounts, or in the breast, especially before breastfeeding, is not recommended.
Mandatory precautions while using betamethasone lotion
If there are no signs of recovery, consult a doctor one week after use.
The skin of the area treated with this lotion in the genital area of children should not be covered without a doctor’s opinion
1- This medicine should not be used in untreated bacterial, fungal or viral skin lesions, rosacea disease (daily acne) and perioral skin inflammation, ulcerated or itchy inflammatory conditions. It is not recommended to prescribe this drug for the treatment of acne vulgaris (especially strong corticosteroids are contraindicated).
2- Strong corticosteroids are contraindicated in children under one year old.
Warnings regarding the use of betamethasone
1- Use this medicine on children’s skin with iodine with great caution.
2- Following the use of this medicine, tests to check the function of the hypothalamus-pituitary-adrenal axis may be disturbed.
3- Consuming amounts of more than 100 grams per week of 0.1% of Faravar Ten is probably associated with the weakening of the adrenal gland.
4- In order to minimize the side effects of topical corticosteroids, it is necessary to use the drug as a thin layer and only in the required areas up to twice a day.
5- Long-term use of the product on the skin of the face should be avoided.
Side effects of betamethasone
Due to the low metabolism of betamethasone in the skin, the possibility of its systemic absorption is high, and therefore the occurrence of complications such as Cushing’s syndrome, increased blood sugar, the presence of sugar in the urine, and in the long term weakening of the hypothalamus-pituitary-adrenal gland axis is possible.
Recommended points regarding the use of betamethasone
1- It should be avoided to use a cover or dressing on the area under betamethasone treatment.
2- If after two weeks the complication for which betamethasone was prescribed did not improve or worsened, the doctor must be informed.
3- Before breastfeeding, the use of this medicine on the breast tissue should be avoided.
4- The use of medicine around the eyes should be avoided.
5- Betamethasone lotion should be shaken well before use.
Betamethasone lotion storage conditions
Store the medicine at a temperature below 30 degrees Celsius and protect it from freezing.
Keep the medicine out of the reach of children.
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