Aluminium MGS

What is MGS Aluminum?

Aluminum MGS is a combination of aluminum hydroxide, magnesium hydroxide and simethicone drugs.

Aluminum hydroxide is an inorganic salt that is used as an antacid. Its effectiveness is by neutralizing the hydrochloric acid of the digestive juice, as a result, by increasing the pH of the stomach, it inhibits pepsin. It probably has a protective effect by increasing bicarbonate and prostaglandin ions.

Magnesium hydroxide: an inorganic compound used as an antacid or laxative in syrup or tablets.

Simethicone: It is an oral decongestant with a local effect that is not absorbed by the body. It is used in excessive bloating. It is a mixture of polydimethylsiloxane and hydrated silica gel.

Mechanism of effect of MGS aluminum

Aluminum hydroxide: neutralizing stomach acid and creating AlCl3 salt and water and increasing stomach pH.

Magnesium hydroxide: with its osmotic effect and liquid absorption, it increases bowel movement and emptying. It creates magnesium chloride in reaction with acid.

Simethicone: By reducing surface tension, it causes gas bubbles to disappear.

Pharmacodynamics of Aluminum MGS

Aluminum hydroxide: Gastric-peptic diseases are due to the imbalance of protective factors such as mucus, bicarbonate and prostaglandin and harmful factors such as hydrochloric acid, pepsin and Helicobacter pylori. Antacids reduce the activity of pepsin and increase secretion by establishing the acid-base balance. bicarbonate and prostaglandin.

Magnesium Hydroxide: neutralizes hydrochloric acid, as a result, the pH of the stomach increases and deactivates pepsin. It strengthens the mucous barrier of the stomach and increases the contraction of the gastric and esophageal sphincters.

Simethicone: By reducing the surface tension of gas bubbles, it causes them to shrink and reduce bloating. It also inhibits the formation of mucous gas bubbles.

Pharmacokinetics of Aluminum MGS

Aluminum and magnesium hydroxide: the ion absorbed from the digestive system is excreted in the urine, and its insoluble salts are excreted in the intestine through feces.

Pharmacokinetics of Aluminum MGS

Aluminum and magnesium hydroxide: the ion absorbed from the digestive system is excreted in the urine, and its insoluble salts are excreted in the intestine through feces.

MGS aluminum consumption


Indigestion, flatulence

10-20 ml orally every 4-6 hours, one hour before or three hours after eating


2-4 tablets should be chewed every 4-6 hours. Do not take more than 12 tablets in 24 hours.


The safety of this drug in children has not been confirmed.

prohibited usage

Hypersensitivity to this drug or its ingredients

MGS aluminum side effects

Diarrhea, nausea, constipation, vomiting, hypophosphatemia, hypermagnesemia, chalky taste in the mouth, stool hardness, stomach cramps, increased secretion of acid reflux, aluminum toxicity, milk-alkaline syndrome, osteomalacia.

Drug interactions

Atomoxetine, Itraconazole, Tetracycline, Dapsone, Doxycycline, Digoxin, Minocycline, Raltegravir, Oxytetracycline, Nimodipine, Ketoconazole, Atazanavir, Intravenous Potassium Phosphate, Indinavir, Norfloxacin, Erlotinib, Ofloxacin, Gemifloxacin, Ciprofloxacin, Mofoxil, Mycofloxacin , Nalidixic acid, Hematogel, Rosuvastatin


Kidney failure

They may affect the absorption of other drugs by changing the conditions of the gastrointestinal tract or by direct binding.

Low magnesium diet

Do not use combination products to treat hyperphosphatemia.

Recommended tips

Talk to your doctor if you are on a low-magnesium diet.
Do not take this medicine for longer than prescribed by the doctor.
Some oral medications should be taken at a distance from this medication. Talk to your doctor.
Talk to your doctor if you have phenylketonuria. Some products contain phenylalanine.
Talk to your doctor if you are pregnant or breastfeeding.
Chew the tablet thoroughly before swallowing.
Most of the time, this medicine is used only in cases of need. Do not take more than the amount prescribed by the doctor.

Use in pregnancy

C (Group C drugs should only be used with a doctor’s prescription. The risks of using this group of drugs have not yet been ruled out, or human studies have not been conducted, and when the doctor feels that the benefits of using this group of drugs outweigh the possible harms. It is much more, and its consumption is necessary for the patient to prescribe.)

Similar drugs

Calcium carbonate, aluminum hydroxide, charcoal


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