Painkiller, antipyretic, anti-inflammatory
Suspension 100 mg in 5 ml
The mechanism of action:
Indications of advalgin:
Relief of pain and fever caused by cold and flu, relief of pain and fever caused by vaccination, relief of pain and fever caused by tooth extraction, joint pain and rheumatoid arthritis.
Use in pregnancy and breastfeeding:
Pregnancy: Adequate and well-controlled studies have not been conducted in pregnant women. The use of this medicine during pregnancy should be done under the supervision of a specialist and with caution.
Lactation: This drug is secreted in a small amount in breast milk. Therefore, its use during breastfeeding should be done with the doctor’s opinion.
Pay attention to these points regarding the correct way of consumption:
- Use this medicine only according to the doctor’s prescription or the medicine guide. Avoid taking more amounts or more often than prescribed by the doctor or the drug guide. Unless prescribed by a doctor.
- In order to reduce digestive irritation, take the medicine with food or milk.
- Shake the bottle well before each use.
- If you forget to take a dose of medicine, take it as soon as you remember. But if it is almost time to take the next dose, take only that dose and avoid doubling the amount of medicine.
Drug interactions of advalgin:
Before taking this medicine, if you use the following medicines. Inform your doctor:
Alcohol, oral corticosteroids, corticotropin – the risk of serious stomach problems such as ulcers and bleeding may increase.
Anticoagulants (such as warfarin and heparin) – the risk of bleeding may increase.
Aspirin – If aspirin and ibuprofen are used simultaneously and continuously, the possibility of serious side effects increases.
Cyclosporine, tacrolimus, digitalis glycosides, litbi, methotrexate, phenytoin increase the amount of these drugs in the blood and also the possibility of side effects.
Enalapril, gaptopril, losartan, beta-blockers (such as atenolol, propranolol) – taking these drugs together with ibuprofen may reduce their blood pressure-lowering effects.
probenecid The amount of ibuprofen in the blood and the possibility of side effects increase.
Diuretics (such as the need for potassium-sparing diuretics and loop diuretics) – the combined use of these drugs with ibuprofen may decrease the diuretic effects and increase the risk of acute renal failure.
Triamterene – the chance of kidney problems may increase.
Quinolone antibiotics (such as ciprofloxacin) – the risk of central nervous system irritation and seizures may be increased with these antibiotics. At the same time, the plasma concentrations of these antibiotics also increase. Caution is essential.
Selective serotonin reuptake inhibitors (such as fluoxetine, venlafaxine) – concomitant use of drugs may increase the antiplatelet effect of ibuprofen and increase the risk of gastrointestinal bleeding, while the therapeutic effect of selective serotonin reuptake inhibitors may also decrease.
Precautions of advalgin:
1- If you take this medicine for a long time. In order to control the progress of the treatment, visit the doctor at regular intervals. The doctor may prescribe some tests to check the occurrence of some unwanted side effects. These tests are important because serious side effects, including ulcers, bleeding, or blood disorders, can occur without warning.
2- Simultaneous use of this medicine with large amounts of alcoholic beverages may cause stomach problems.
3- Simultaneous and continuous use of this drug with other non-steroidal anti-inflammatory drugs may increase the possibility of unwanted effects. Also, simultaneous use of acetaminophen, aspirin with other salicylates or ketorolac with this drug may increase the risk of adverse effects. The amount of risk depends on the daily intake of each drug and the duration of simultaneous use of the drugs.
4- Treatment with this drug can cause serious side effects. Sometimes these complications can be without symptoms. Although warning signs such as swelling of the face, toes and lower legs, severe stomach pain, black and fetid stools, vomiting blood or substances similar to coffee beans, abnormal weight gain and skin rashes often occur. There may also be serious symptoms of heart diseases such as chest pain, a feeling of shame in the chest, fast or irregular heartbeat, unusual hot flashes or skin warmth. In such cases, immediately stop taking the medicine and contact your doctor.
5- Before performing any surgery (including dental surgery or other urgent medical treatments), inform your doctor and dentist about the use of this medicine.
6- This drug may cause confusion, drowsiness, confusion, dizziness and loss of consciousness in some people. It may also cause blurring of vision with other vision problems in some people, so it is recommended to be careful before driving and working with equipment that requires full alertness.
7- Some people may be more sensitive to sunlight while taking this medicine. Exposure to sunlight, even for a short time, may cause severe sunburn, blisters on the skin, skin rashes, redness, itching, or changes in skin color and vision changes.
8- If you see tremors, pain with muscle spasms and other flu-like symptoms, especially if accompanied by skin rashes, consult your doctor immediately. These effects may rarely be the first symptoms of serious drug side effects.
9- Taking this medicine may cause a serious allergic reaction called anaphylaxis. This reaction often occurs in patients who are allergic to aspirin and other non-steroidal anti-inflammatory drugs. Anaphylaxis requires immediate medical treatment. The most common symptoms of this reaction are fast or irregular breathing, wheezing, and syncope. Other symptoms include facial skin color change, rapid or irregular heartbeat, urticaria-like swelling of the skin, and swelling of the eyelids. In such a situation, urgent medical treatment is required immediately.
10- If the symptoms do not improve or worsen, if you observe a high fever or a fever that lasts for more than 3 days, and redness or swelling of the painful area, consult your doctor.
prohibited usage of advalgin:
1- History of allergy to ibuprofen or any of the components of this medicine
2- A history of severe allergic reaction such as rhinitis, urticaria, runny nose, anaphylaxis or angioedema due to the use of aspirin with other non-steroidal anti-inflammatory drugs.
3- Bitty polyps with bronchial contraction caused by aspirin consumption
4- Simultaneous use with aspirin with a daily dose of more than 75 mg and other non-steroidal anti-inflammatory drugs
5- History of ulcer, perforation or stomach bleeding
6- Severe kidney, liver and heart failure
7- Children weighing less than 5 kg and less than 3 months old
8- The last trimester of pregnancy
9- Pain relief during heart artery bypass surgery
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